GENERAL CATALOGUE
BGC0222
HY-P10783 · 50 mg
MedChemExpress · Cat: HY-P10783
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medchemexpress.com/bgc0222.html
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Catalog No: HY-P10783
Category: Antibody-drug Conjugate ADC Related
Pack Size: 50 mg
Brand: MedChemExpress
Description
BGC0222 is a novel prodrug of Irinotecan HY-16562 . BGC0222, as a PEG-cRGD-conjugated Irinotecan HY-16562 derivative, could slowly and steadily release Irinotecan HY-16562 . BGC0222 binds to ?V?3 with IC50 values of 4.25 ?M ?V?3 and 58.7 ?M ?V?5 . BGC0222 possesses the property of inducing neovascularization. BGC0222 exhibits good antiproliferation activity in many tumors.
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