

HY-150023 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-150023
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medchemexpress.com/bi-1622.htmlDescription
BI-1622 is an orally active, potent and highly selective HER2 ERBB2 inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile.





