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BI-1622
GENERAL CATALOGUE

BI-1622

HY-150023 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-150023

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medchemexpress.com/bi-1622.html
Catalog No: HY-150023
CAS No: 2681392-19-6
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

BI-1622 is an orally active, potent and highly selective HER2 ERBB2 inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile.

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