GENERAL CATALOGUE
BI-2865
HY-153724 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153724
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Manufacturer product page
medchemexpress.com/bi-2865.htmlCatalog No: HY-153724
CAS No: 2937327-93-8
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BI-2865 is a none-covalent pan-KRAS Inhibitor. BI-2865 binds to WT, G12C, G12D, G12V and G13D mutant KRAS with KDs of 6.9, 4.5, 32, 26, 4.3 nM respectively. BI-2865 inhibits the proliferation of G12C, G12D or G12V mutant KRAS expressing BaF3 cells mean IC50: roughly 140 nM .
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