GENERAL CATALOGUE
BI-3406
HY-125817 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-125817
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Manufacturer product page
medchemexpress.com/sos1-in-2.htmlCatalog No: HY-125817
CAS No: 2230836-55-0
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
BI-3406 compound I-6 is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 SOS1 with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity.
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