GENERAL CATALOGUE
BI-4924
HY-126254 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-126254
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Manufacturer product page
medchemexpress.com/bi-4924.htmlCatalog No: HY-126254
CAS No: 2244452-09-1
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase PHGDH inhibitor IC50=3 nM with excellent microsomal, as well as hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis with an IC50 of 2200 nM at 72 h.
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