BI 653048 phosphate

Description

BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid GC agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoformsAAasAasAa activity and reduces affinity for the hERG ion channel IC50 30 ?M. BI 653048 phosphate is extracted from patent WO2005028501A1 Compound 103 , is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.