GENERAL CATALOGUE
(-)BI97D6
HY-115529 · 50 mg
MedChemExpress · Cat: HY-115529
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Manufacturer product page
medchemexpress.com/minus-bi97d6.htmlCatalog No: HY-115529
CAS No: 1430067-36-9
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
- BI97D6 is a broad-spectrum inhibitor of the Bcl-2 protein family, inhibiting Mcl-1, Bcl-2, Bcl-xL and Bcl-1 with IC50 values of 0.025, 0.031, 0.076 and 0.122 ?M, respectively. - BI97D6 stimulates cell death through the Bak and Bax mediated mitochondrial apoptosis pathway. In addition, - BI97D6 inhibits Mcl-1 and can effectively induce apoptosis in acute myeloid leukemia AML cells.
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