GENERAL CATALOGUE
Bifendate
HY-W018791 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W018791
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Catalog No: HY-W018791
CAS No: 73536-69-3
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Bifendate DDB , extracted from Schisandrae chinensis, is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase ALT level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins CYPs and reverse P-gp-mediated multi-drug resistance MDR .
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