

HY-101986 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-101986
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medchemexpress.com/BIIE-0246.htmlDescription
BIIE-0246 AR-H 053591 is a potent and selective NPY2R neuropeptide Y receptor 2 antagonist with an IC50 value of 15 nM for rat 125I PYY3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy.







