GENERAL CATALOGUE
BIIE-0246 hydrochloride
HY-101986A · 1 mg
MedChemExpress · Cat: HY-101986A
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medchemexpress.com/biie-0246-hydrochloride.html
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Catalog No: HY-101986A
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
BIIE-0246 hydrochloride AR-H 053591 hydrochloride is a potent and selective NPY2R neuropeptide Y receptor 2 antagonist with an IC50 value of 15 nM for rat 125I PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy.
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