BinCARD Rabbit Polyclonal Antibody

Description

EnkiLife offers the BinCARD Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: C9orf89; Bcl10-interacting CARD protein; BinCARD. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: IHC 1:100-1:300,ICC/IF 1:50-1:200,ELISA 1:20000-1:40000 Background: function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner. PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR. similarity:Contains 1 CARD domain. subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol. subunit:Associates with BCL10 by CARD-CARD interaction. tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.