GENERAL CATALOGUE
BIO-7488
HY-162359 · 5 mg
MedChemExpress · Cat: HY-162359
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medchemexpress.com/bio-7488.htmlCatalog No: HY-162359
CAS No: 2573211-25-1
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
BIO-7488 is an orally active, selective and blood-brain barrier permeable IRAK4 inhibitor, with an IC50 value of 0.5 nM. BIO-7488 inhibits the production of pro-inflammatory cytokines IL-1?, TNF?, IL-6 and demonstrates anti-inflammatory effects in both LPS HY-D1056 and distal hypoxic-middle cerebral artery occlusion DH-MCAO ischemic stroke model. BIO-7488 can be used for the study of neuroinflammatory-related diseases, particularly ischemic stroke.
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