GENERAL CATALOGUE
BIO-8169
HY-158374 · 50 mg
MedChemExpress · Cat: HY-158374
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Manufacturer product page
medchemexpress.com/bio-8169.htmlCatalog No: HY-158374
CAS No: 2792153-06-9
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
BIO-8169 is a selective inhibitor for interleukin receptor-associated kinase 4 IRAK 4 , with an IC50 of 0.23 nM. BIO-8169 exhibits good pharmacokinetic character, reduces the production of pro-inflammatory cytokines, and attenuates the autoimmune encephalomyelitis in EAE mice model. BIO-8169 exhibits good blood brain penetrant with a rat Kpu,u of 0.7.
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