GENERAL CATALOGUE
Bisindolylmaleimide VIII
HY-129624 · 50 mg
MedChemExpress · Cat: HY-129624
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Catalog No: HY-129624
CAS No: 125313-65-7
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Bisindolylmaleimide VIII Ro 31-7549 is a potent and selective protein kinase C PKC inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII has IC50s of 53, 195, 163, 213, and 175 nM for PKC-?, PKC-?I, PKC-?II, PKC-?, PKC-?, respectively. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.
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