GENERAL CATALOGUE
BIX-01294
HY-10587 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10587
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medchemexpress.com/BIX-01294.html
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Catalog No: HY-10587
CAS No: 935693-62-2
Category: Autophagy
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 ?M and 0.9 ?M, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a 1H-1,4-diazepin-1-yl -quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells.
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