GENERAL CATALOGUE
BM-1244
HY-138832 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138832
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medchemexpress.com/bm-1244.html
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Catalog No: HY-138832
CAS No: 1619923-32-8
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BM-1244 APG-1252-M1 is a Bcl-xL/Bcl-2 inhibitor with Kis of 134 nM and 450 nM. BM-1244 has anti-tumor effects by inducing apoptosis and suppressing tumor growth. BM-1244 can induce cytochrome C and Smac release from mitochondria with caspase-3 and PARP cleavage. BM-1244 exhibits synergy with chemotherapy in vivo. BM-1244 can be studied in research for colorectal cancer, acute myeloid leukemia and gastric cancer.
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