GENERAL CATALOGUE
BM213
HY-145237 · 5 mg
MedChemExpress · Cat: HY-145237
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Catalog No: HY-145237
CAS No: 2891606-02-1
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
BM213 is a selective C5aR agonist, with an EC50 of 59 nM. BM213 specifically activates the C5a-C5aR1 axis, which in turn promotes neutrophil extracellular trap NET formation and exacerbates inflammatory responses. BM213 significantly induces ventricular dilationin, promotes myocardial ROS production, and induces cardiomyocyte apoptosis in rats. BM213 can be used for the study of myocardial ischemia/reperfusion I/R injury.