GENERAL CATALOGUE
BML-278
HY-W025074 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-W025074
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medchemexpress.com/bml-278.htmlCatalog No: HY-W025074
CAS No: 120533-76-8
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BML-278 is a SIRT1 activator EC150: 1 ?M . BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in both the paternal and maternal pronucleus. BML-278 improves early embryonic development. BML-278 arrests the cell cycle at the G1/S phase, and reduces senescence in primary human mesenchymal cells. BML-278 reduces tubulin acetylation in U937 cells. BML-278 also increases mitochondrial density in murine C2C12 myoblasts.
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