BMP4 Mouse Monoclonal Antibody

Description

EnkiLife offers the BMP4 Mouse Monoclonal Antibody. This antibody reacts with Human,Rat species and is suitable for WB,ICC,ELISA application. Alternative Names of Immunogen: ZYME; BMP2B; OFC11; BMP2B1; MCOPS6. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ICC 1:100-1:500,ELISA 1:5000-1:20000 Background: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. Research Area: TGF-beta signaling pathway