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BMS-1166 hydrochloride
GENERAL CATALOGUE

BMS-1166 hydrochloride

HY-102011A · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-102011A

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Catalog No: HY-102011A
CAS No: 2113650-05-6
Category: Immunology Inflammation
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

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