GENERAL CATALOGUE
BMS-214662 hydrochloride
HY-16111A · 1 mg
MedChemExpress · Cat: HY-16111A
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medchemexpress.com/bms-214662-hydrochloride.htmlCatalog No: HY-16111A
CAS No: 195981-08-9
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress
Description
BMS-214662 hydrochloride is an inhibitor of farnesyltransferase Farnesyl Transferase . BMS-214662 hydrochloride can effectively block the localization and function of Ras proteins on the cell membrane by inhibiting the prenylation modification of Ras proteins, thereby exerting anti-tumor activity. The IC50 value of BMS-214662 hydrochloride for H-Ras is 1.3 nM, and for K-Ras it is 8.4 nM. BMS-214662 hydrochloride can be used in the research of tumor diseases related to Ras.
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