GENERAL CATALOGUE
BMS-37
HY-150879 · 5 mg
MedChemExpress · Cat: HY-150879
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Catalog No: HY-150879
CAS No: 1675202-20-6
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
BMS-37 is a PD-1/PD-L1 immune checkpoint inhibitor with an IC50 towards the PD-L1/PD-1 complex in the range of 18 to 200 nM. BMS-37 shows unspecific toxicity against modified Jurkat T cells with an EC50 between 3 and 6 AAasAasAAmuM. BMS-37 can be used for the study of the PD-L1-induced exhaustion of T-cells or as PD-L1 ligand to synthesize PROTAC molecules.
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