GENERAL CATALOGUE
BMS-599626 Hydrochloride
HY-12010 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12010
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Manufacturer product page
medchemexpress.com/BMS-599626-Hydrochloride.htmlCatalog No: HY-12010
CAS No: 873837-23-1
Category: JAK STAT Signaling
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
BMS-599626 Hydrochloride AC480 Hydrochloride is a selective and orally bioavailable HER1 and HER2 inhibitor, with IC50s of 20 and 30 nM, respectively. BMS-599626 Hydrochloride displays 8-fold less potent to HER4 IC50=190 nM , >100-fold to VEGFR2, c-Kit, Lck, MEK. BMS-599626 Hydrochloride inhibits tumor cell proliferation, and has potential to increase tumor response to radiotherapy.
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