GENERAL CATALOGUE
BMS-984923
HY-122559 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-122559
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Manufacturer product page
medchemexpress.com/bms-984923.htmlCatalog No: HY-122559
CAS No: 1375752-78-5
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BMS-984923, a potent mGluR5 silent allosteric modulator SAM , with exquisite binding affinity Ki = 0.6 nM , exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological A?o signaling without affecting physiological glutamate signaling.
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