GENERAL CATALOGUE
BMS-986251
HY-136527 · 50 mg
MedChemExpress · Cat: HY-136527
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Catalog No: HY-136527
CAS No: 2460133-35-9
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
BMS-986251 is an orally active and selective ROR?t inverse agonist with an EC50 of 12 nM for ROR?t GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced HY-B0180 models preclinical models of psoriasis .
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