GENERAL CATALOGUE
BMS-986458
HY-172736 · 5 mg
MedChemExpress · Cat: HY-172736
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Catalog No: HY-172736
CAS No: 3005272-36-3
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
BMS-986458 is a highly selective and orally active BCL6 PROTAC degrader. BMS-986458 simultaneously co-opts cereblon CRBN and the BCL6 N-terminal BTB domain to catalyze proximity induced degradation of BCL6. BMS-986458 can be used for the study of B-cell Non-Hodgkins lymphoma Pink: Target protein ligand HY-172740 ; Black: linker HY-W267161 ; Blue: E3 ligase ligand HY-W593794 .
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