GENERAL CATALOGUE
BMS-P5
HY-137655 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-137655
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Catalog No: HY-137655
CAS No: 1549811-36-0
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BMS-P5 is a selective and orally active peptidylarginine deiminase 4 PAD4 inhibitor with an IC50 of 98 nM. BMS-P5 shows selective for PAD4 over PAD1, PAD2, and PAD3. BMS-P5 blocks multiple myeloma MM -induced neutrophil extracellular trap NET formation and delays progression of MM in a syngeneic mouse model.
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