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BMS202 (PD-1/PD-L1 inhibitor 2), small-molecule inhibitor
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BMS202 (PD-1/PD-L1 inhibitor 2), small-molecule inhibitor

ab231311 · 1 mg

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Catalog No: ab231311
Category: Biochemicals
Pack Size: 1 mg
Brand: abcam

Description

MW 419.5 Da, Purity >98 %. PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor with an IC50 of 18 nM. Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.

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