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BMSpep-57 hydrochloride
GENERAL CATALOGUE

BMSpep-57 hydrochloride

HY-P3143A · 1 mg

MedChemExpress · Cat: HY-P3143A

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Catalog No: HY-P3143A
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress

Description

BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs.

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