GENERAL CATALOGUE
Bohemine
HY-12843 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-12843
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medchemexpress.com/bohemine.htmlCatalog No: HY-12843
CAS No: 189232-42-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 ?M, 83 ?M, and 2.7 ?M for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 ?M and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities.
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