GENERAL CATALOGUE
Bortezomib-d8
HY-10227S · 100 g
MedChemExpress · Cat: HY-10227S
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medchemexpress.com/bortezomib-d8.htmlCatalog No: HY-10227S
Category: Apoptosis
Pack Size: 100 g
Brand: MedChemExpress
Description
Bortezomib-d8 is the deuterium labeled Bortezomib. Bortezomib PS-341 is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome Ki=0.6 nM by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-?B. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma MM . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages TAMs .
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