GENERAL CATALOGUE
Bortezomib
HY-10227 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10227
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Catalog No: HY-10227
CAS No: 179324-69-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Bortezomib PS-341 is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome Ki=0.6 nM by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-AZAoB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma MM . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages TAMs .
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