GENERAL CATALOGUE
BPTQ
HY-124122 · 50 mg
MedChemExpress · Cat: HY-124122
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medchemexpress.com/bptq.html
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Catalog No: HY-124122
CAS No: 1802665-43-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
BPTQ is a potent inhibitor against VEGFR1 and CHK2 with IC50 values of 0.54 and 1.70 AAasAasAAmumol/L, respectively. BPTQ is also an intercalator of DNA with anticancer activities. BPTQ inhibits the proliferation of HL-60 cells by arresting cells at S and G2/M phase with an IC50 value of 12 AAasAasAAmumol/L. BPTQ also activates the mitochondria-mediated Apoptosis pathway by a decrease in mitochondrial membrane potential, increase in the Bax:Bcl-2 ratio and activation of caspases.
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