GENERAL CATALOGUE
Branaplam hydrochloride
HY-19620A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19620A
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medchemexpress.com/branaplam-hydrochloride.htmlCatalog No: HY-19620A
CAS No: 1562338-39-9
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Branaplam LMI070; NVS-SM1 hydrochloride is a highly potent, selective and orally active survival motor neuron-2 SMN2 splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene hERG with an IC50 of 6.3 ?M. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy SMA mouse model.
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