GENERAL CATALOGUE
BRD-810
HY-162858 · 1 mg
MedChemExpress · Cat: HY-162858
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Catalog No: HY-162858
CAS No: 2329719-65-3
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
BRD-810 is a potent and selective MCL1 inhibitor with a Kd of 0.3 nM. BRD-810 can specifically block the BH3 binding groove of MCL1, while having little effect on other anti-apoptotic proteins such as Bcl-2, Bcl-xL . BRD-810 effectively destroys the MCL1-BAK complex IC50 = 1.2 nM in cancer cells, rapidly activates Caspase and induces cell apoptosis. BRD-810 can be used in the research of various cancers such as hematological tumors and solid tumors.
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