

HY-19618 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-19618
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Manufacturer product page
medchemexpress.com/brd3308.html
Description
BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 IC50 of 1.26 ?M or HDAC2 IC50 of 1.34 ?M . BRD3308 suppresses pancreatic ?-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency.







