GENERAL CATALOGUE
BRD4/CK2-IN-1
HY-145260 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-145260
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Manufacturer product page
medchemexpress.com/brd4-ck2-in-1.htmlCatalog No: HY-145260
CAS No: 2756851-99-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
BRD4/CK2-IN-1 is the first highly effective and oral active dual-target inhibitor of BRD4/CK2 bromodomain-containing protein 4/casein kinase 2 , with IC50s of 180 nM and 230 nM for BRD4 and CK2, respectively. BRD4/CK2-IN-1 has strong anticancer activity without obvious toxicities. BRD4/CK2-IN-1 induces apoptosis and autophagy-associated cell death in triple-negative breast cancer TNBC
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