BRD4 Inhibitor-40

Name: BRD4 Inhibitor-40
Brand: MedChemExpress

HY-173062 · 50 mg

MedChemExpress · Cat: HY-173062

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Manufacturer product page

medchemexpress.com/brd4-inhibitor-40.html

Catalog No: HY-173062

CAS No: 2994635-04-8

Category: Apoptosis

Pack Size: 50 mg

Brand: MedChemExpress

Description

BRD4 Inhibitor-40 Compound 23 is the inhibitor for BRD that inhibits BRD4-BD1, BRD4-BD2, BRD2-BD1 and BRD2-BD2 with IC50s of 16.1, 142.18, 29.35 and 302.35 nM, respectively. BRD4 Inhibitor-40 modulates the expression of c-Myc and p21, arrests cell cycle at G1 phase, inhibits Pkd1-null PN renal cystic epithelial cells, and blocks the renal cysts formation in Madin-Darby canine kidney and embryonic kidney vesicle models. BRD4 Inhibitor-40 exhibits renal cysts inhibitory activity in mouse models.