GENERAL CATALOGUE
BRD6257
HY-173084 · 50 mg
MedChemExpress · Cat: HY-173084
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Catalog No: HY-173084
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
BRD6257 is an orally active inhibitor for protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D with an IC50 of 5 nM. BRD6257 activates p53 signaling pathway with an EC50 of 51 nM, increases the p21 expression, inhibits the proliferation of cancer cell MOLM13 IC50=2.8 ?M . BRD6257 exhibits good metabolic stability in human and rat liver microsomes.
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