GENERAL CATALOGUE
BRD6989
HY-122586 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-122586
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Catalog No: HY-122586
CAS No: 642008-81-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BRD6989, an analog of the natural product cortistatin A dCA , inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of 200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes.
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