

HY-138967 · 50 mg
MedChemExpress · Cat: HY-138967
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medchemexpress.com/brf110.html
Description
BRF110 is the selective, orally active rexinoid for Nurr1-RXR?, that selectively activates the Nurr1-RXR? heterodimer with an EC50 of 0.9 ?M in SH-SY5Y. BRF110 upregulates the expression of BDNF, exhibits neuroprotective activity against MPP+ induced toxicity. BRF110 can cross blood-brain barrier.







