GENERAL CATALOGUE
Brophenexin free base
HY-139192A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139192A
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medchemexpress.com/nmdar-trpm4-in-2-free-base.html
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Catalog No: HY-139192A
CAS No: 1353979-43-7
Category: MAPK ERK Pathway
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Brophenexin free base compound 8 is a potent NMDAR/TRPM4 interaction interface inhibitor. Brophenexin free base shows neuroprotective activity. Brophenexin free base prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 ?M. Brophenexin free base protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
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