GENERAL CATALOGUE
BS-181 dihydrochloride
HY-110368 · 50 mg
MedChemExpress · Cat: HY-110368
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medchemexpress.com/bs-181-dihydrochloride.htmlCatalog No: HY-110368
CAS No: 1883548-83-1
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
BS-181 dihydrochloride is a potent and selective CDK7 inhibitor IC50=21 nM than Seliciclib HY-30237 . BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively fails to block CDK1, 4 and 6 . BS-181 dihydrochloride inhibits a panel of cancer cells growth IC50=11.5 ?M-37.3 ?M and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy.
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