GENERAL CATALOGUE
BS-181
HY-13266 · 5 mg
MedChemExpress · Cat: HY-13266
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Catalog No: HY-13266
CAS No: 1092443-52-1
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
BS-181 is a potent and selective CDK7 inhibitor IC50=21 nM than Seliciclib HY-30237 . BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively fails to block CDK1, 4 and 6 . BS-181 inhibits a panel of cancer cells growth IC50=11.5 ?M-37.3 ?M and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy.
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