GENERAL CATALOGUE
BSc5367
HY-144425 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-144425
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Catalog No: HY-144425
CAS No: 3029584-84-4
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis ALS , polycystic kidney disease PKD and several types of radiotherapy resistant cancer.
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