GENERAL CATALOGUE
BSJ-02-162
HY-144995 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-144995
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medchemexpress.com/cdk4-6-in-11.htmlCatalog No: HY-144995
CAS No: 2139329-47-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
CDK4/6-IN-11 is a potent PROTAC CDK4/6 degrader. CDK4/6-IN-11 consists of a thalidomide-based E3 ligase ligand blue part Thalidomide-NH-CH2-COOH HY-131717 , a target protein ligand red part Palbociclib HY-50767 , and a PROTAC linker black part Boc-NH-C4-Br HY-W007803 . E3 ligase ligand and linker can form Thalidomide-NH-amido-C4-Br HY-170307 .