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BSJ-03-204
GENERAL CATALOGUE

BSJ-03-204

HY-136250 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-136250

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Manufacturer product page

medchemexpress.com/bsj-03-204.html
Catalog No: HY-136250
CAS No: 2349356-09-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

BSJ-03-204 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-03-204 is a potent and selective Palbociclib-based CDK4/6 dual degrader PROTAC , with IC50s of 26.9 nM and 10.4 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-03-204 does not induce IKZF1/3 degradation and has anti-cancer activity.

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