GENERAL CATALOGUE
BSJ-04-132
HY-136252 · 5 mg
MedChemExpress · Cat: HY-136252
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medchemexpress.com/bsj-04-132.htmlCatalog No: HY-136252
CAS No: 2349356-39-2
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
BSJ-04-132 is a PROTAC connected by ligands for Cereblon and CDK. BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader PROTAC , with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity.
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