GENERAL CATALOGUE
BSJ-5-63
HY-162706 · 5 mg
MedChemExpress · Cat: HY-162706
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medchemexpress.com/bsj-5-63.htmlCatalog No: HY-162706
CAS No: 2519823-37-9
Category: Cell Cycle DNA Damage
Pack Size: 5 mg
Brand: MedChemExpress
Description
BSJ-5-63 is a potent CDK12, CDK7, CDK9 PROTAC degrader. BSJ-5-63 BSJ-5-63 decreases the protein expression of CDK12, CDK7, CDK9, RNAPII, Cyclin K. BSJ-5-63 decreases the mRNA expression of BRCA1, BRCA2. BSJ-5-63 shows anticancer activity and has the potential for the research of prostate cancer Pink: ligand for target protein HY-150948 ; black: linker HY-W140827 ; Blue: E3 ligase ligand HY-112078 .