GENERAL CATALOGUE
BTI-322
HY-P991543 · 1 mg
MedChemExpress · Cat: HY-P991543
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Catalog No: HY-P991543
CAS No: 339181-10-1
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
BTI-322 is a rat monoclonal IgG2b directed against the CD2 antigen on T cells and NK cells. BTI-322 can block primary and memory alloantigen proliferative responses in vitro. BTI-322 recognizes over 90 % of E-rosette-forming peripheral blood lymphocytes and T-cell leukemias. BTI-322 has immunosuppressive activity. BTI-322 effectively inhibits T cell responses in vitro to allogeneic cells. BTI-322 can be used as a T-cell deplting agent. BTI-322 can be studied in research for renal allograft rejection and steroid-refractory acute graft-versus-host disease.
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